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XDH Polyclonal antibody, PBS Only

XDH Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 55156-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

xanthine dehydrogenase, Xanthine Oxidase, Xanthine oxidoreductase, XD, XDHA

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

55156-1-PBS targets XDH in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

Peptide

Predict reactive species
Full Name xanthine dehydrogenase
Calculated Molecular Weight 146 kDa
Observed Molecular Weight 147-150 kDa
GenBank Accession NumberNM_000379
Gene Symbol XDH
Gene ID (NCBI) 7498
RRIDAB_10860905
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDP47989
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

XDH, also named as XDHA, XO and XD, belongs to the xanthine dehydrogenase family. It catalyzes the last two steps of purine catabolism in man, formation of the end product uric acid from hypoxanthine and xanthine. The mammalian enzyme is synthesized as a dehydrogenase (XDH), which uses NAD as the electron acceptor, but it can be converted into an oxidase (XO) both in vivo and in vitro.This gene encodes a protein of 150 kDa and the 150 kDa polypeptide can be processed into a fragment of 130 kDa and further to 85 kDa by spontaneous proteolytic cleavage(PMID:9989587). In addition, the full length polypeptide can be also partially processed into a 87 kDa and 59 kDa fragments(PMID:21528298). It also can exsit as a homodimer(PMID:9989587).

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