humanin Polyclonal antibody

humanin Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 25885-1-AP

Synonyms

humanin, l rRNA, MTRNR2, RNR2

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Validation Data Gallery

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  IHC staining of human heart using 25885-1-AP

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 25885-1-AP (humanin Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human heart using 25885-1-AP

  Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 25885-1-AP (humanin Antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human small intestine using 25885-1-AP

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 25885-1-AP (humanin Antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human small intestine using 25885-1-AP

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 25885-1-AP (humanin Antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human colon using 25885-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 25885-1-AP (humanin Antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human colon using 25885-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 25885-1-AP (humanin Antibody) at dilution of 1:50 (under 40x lens).

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Tested Applications

• Positive IHC detected in: human small intestine tissue, human heart tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:20-1:200

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

25885-1-AP targets humanin in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: l-rRNA
• GenBank Accession Number: NC_012920
• Gene Symbol: humanin
• Gene ID (NCBI): 4550
• RRID: AB_2880281
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Humanin, also named as MT-RNR2, is a mitochondrial peptide. It plays a role as a neuroprotective factor. It protects against death induced by multiple different familial Alzheimer disease genes and beta amyloid proteins in Alzheimer disease. Humanin reduces the aggregation and fibrillary formation by suppressing the effect of APP on mononuclear phagocytes and acts by competitively inhibiting the access of FPRL1 to APP.