ATN1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19243-1-AP

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Con: 34 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse testis tissue

Positive IHC detected in:
human ovary tissue, human ovary tissue, human testis tissue

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
atrophin 1

Calculated molecular weight:
125 kDa

Observed molecular weight:
105-110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ATN1

Synonyms
ATN1, atrophin 1, B37, D12S755E, DRPLA, HRS, NOD
Background

ATN1 also known as Atrophin-1 is a protein that in humans is encoded by the ATN1 gene. Dentatorubral pallidoluysian atrophy is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion of a trinucleotide repeat within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat.


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