FITC Anti-human CD44(F10-44-2)

CD44 Monoclonal Antibody for FC

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

FC

Conjugate

FITC Fluorescent Dye

CloneNo.

F10-44-2

Cat no : FITC-65063

Synonyms

CD44, CD44 antigen, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP 1, PGP I, Pgp1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I



Tested Applications

Positive FC detected inHuman peripheral blood lymphocytes

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

FITC-65063 targets FITC CD44 in FC applications and shows reactivity with Human samples.

Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen Purified T cells from human lymph nodes
Full Name CD44 molecule (Indian blood group)
Calculated molecular weight 742aa,82 kDa
Observed molecular weight
GenBank accession number BC004372
Gene symbol CD44
Gene ID (NCBI) 960
Conjugate FITC Fluorescent Dye
Form Liquid
Purification Method Affinity purification
Storage Buffer PBS with 0.1% sodium azide.
Storage ConditionsStore at 2-8oC. Avoid exposure to light.

Background Information

CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.

Protocols

Product Specific Protocols
FC protocol for FITC CD44 antibody FITC-65063Download protocol
Standard Protocols
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