Complement factor B Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66154-1-Ig |CloneNo.: 8D2B6

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Con: 165 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human blood tissue

Positive IHC detected in:
human liver tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Thiophilic Affinity Chromatography

Isotype:
IgM

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
complement factor B

Calculated molecular weight:
86 kDa

Observed molecular weight:
93 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CFB

Synonyms
BF, BFD, C3/C5 convertase, CFAB, CFB, Complement factor B, FB, FBI12, GBG, Glycine rich beta glycoprotein, H2 Bf, PBF2, Properdin factor B
Background

Complement factor B (CFB) is a component of the alternative pathway of complement activation. Complement factor B is cleaved into Ba and Bb by factor D in the presence of C3b. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.


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