CXCR7 Polyclonal antibody

CXCR7 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IF, FC,ELISA

Conjugate

Unconjugated

Cat no : 51024-1-AP

Synonyms



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

51024-1-AP targets CXCR7 in WB, IHC, IF, FC,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name chemokine (C-X-C motif) receptor 7
Calculated molecular weight 362 aa, 41 kDa
Observed molecular weight 50 kDa
GenBank accession numberBC036661
Gene symbol CXCR7
Gene ID (NCBI) 57007
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

CXCR7, also named as CMKOR1, GPR159 and RDC1, belongs to the G-protein coupled receptor 1 family. It is a receptor for CXCL12/SDF1. CXCR7 acts as coreceptor with CXCR4 for a restricted number of HIV isolates. CXCR7 was shown to contribute to neoangiogenesis in prostate cancer and to promote tumor cell proliferation in breast cancer and adenocarcinoma of the lung.

Publications

SpeciesApplicationTitle
humanWB

Tumour Biol

The SDF-1/CXCR4 chemokine axis in uveal melanoma cell proliferation and migration.

Authors - Jianjun Bi
humanWB

J Surg Res

The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma.

Authors - Zhen Liu
WB

Biochem Biophys Res Commun

Monomeric CXCL12 outperforms its dimeric and wild type variants in the promotion of human endothelial progenitor cells' function.

Authors - Shuang Chang
humanIHC

Scand J Gastroenterol

CXCR7 as a chemokine receptor for SDF-1 promotes gastric cancer progression via MAPK pathways.

Authors - Ameng Shi
humanIHC,IF

PLoS One

CXCR7 Is Involved in Human Oligodendroglial Precursor Cell Maturation.

Authors - David Kremer
mouseIHC

PLoS One

Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice.

Authors - Brennecke Patrick P