Validation Data Gallery
|Sample-dependent, check data in validation data gallery|
51024-1-AP targets CXCR7 in WB, IHC, IF, FC,ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Full Name||chemokine (C-X-C motif) receptor 7|
|Calculated molecular weight||362 aa, 41 kDa|
|Observed molecular weight||50 kDa|
|GenBank accession number||BC036661|
|Gene ID (NCBI)||57007|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Aliquoting is unnecessary for -20oC storage.|
CXCR7, also named as CMKOR1, GPR159 and RDC1, belongs to the G-protein coupled receptor 1 family. It is a receptor for CXCL12/SDF1. CXCR7 acts as coreceptor with CXCR4 for a restricted number of HIV isolates. CXCR7 was shown to contribute to neoangiogenesis in prostate cancer and to promote tumor cell proliferation in breast cancer and adenocarcinoma of the lung.
The SDF-1/CXCR4 chemokine axis in uveal melanoma cell proliferation and migration.
J Surg Res
The involvement of CXCR7 in modulating the progression of papillary thyroid carcinoma.
Biochem Biophys Res Commun
Monomeric CXCL12 outperforms its dimeric and wild type variants in the promotion of human endothelial progenitor cells' function.
Scand J Gastroenterol
CXCR7 as a chemokine receptor for SDF-1 promotes gastric cancer progression via MAPK pathways.
CXCR7 Is Involved in Human Oligodendroglial Precursor Cell Maturation.
Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastasis of Intratibial Xenografts in SCID Mice.