Fibronectin Antibody 3 Publications

Mouse Monoclonal| Catalog number: 66042-1-Ig |CloneNo.: 1G10F9

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
human plasma tissue, human brain tissue, human liver tissue

Positive IP detected in:
human plasma tissue

Positive IHC detected in:
human colon cancer tissue, human breast cancer tissue

Positive IF detected in:
NIH/3T3 cells

Recommended dilution:
WB : 1:2000-1:12000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:300-1:1200
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
fibronectin 1

Calculated molecular weight:
2386aa,263 kDa

Observed molecular weight:
263 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FN1

Synonyms
CIG, Cold insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, DKFZp686O13149, ED B, Fibronectin, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF
Background

Fibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis. (PMID: 7276612; 12244123; 12847088)


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