GSNOR,ADH5 Antibody 22 Publications

Rabbit Polyclonal| Catalog number: 11051-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 21 μg/150 μl

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Species specificity:
human, mouse, rat, chicken

Positive WB detected in:
mouse kidney tissue, human brain tissue, human heart tissue, human liver tissue, mouse brain tissue, mouse kidney tissue

Positive IHC detected in:
human prostate cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
alcohol dehydrogenase 5 (class III), chi polypeptide

Calculated molecular weight:
40 kDa

Observed molecular weight:
40 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADH5

Synonyms
ADH 3, ADH5, ADHX, Alcohol dehydrogenase 5, Alcohol dehydrogenase class 3, FALDH, FDH, GSH FDH, GSNOR
Background

ADH5, also named as ADHX, FDH FALDH GSH-FDH ADH3 and GSNOR, belongs to the zinc-containing alcohol dehydrogenase family and Class-III subfamily. It is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. ADH5 mediates multiple cardiovascular functions. It plays in regulating heterocellular communication in the artery wall. (PMID:21071693). ADH5 immunostaining is distributed in both the nucleus and cytoplasm of the retinal ganglion cells(PMID:22117533).


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