HLA class I ABC Antibody 3 Publications

Mouse Monoclonal| Catalog number: 66013-1-Ig |CloneNo.: 5C5B7

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Con: 166 μg/150 μl

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Species specificity:
human, pig

Positive WB detected in:
HeLa cells, HepG2 cells, Raji cells, U-937 cells

Positive IHC detected in:
human tonsillitis tissue, human heart tissue, human spleen tissue, human tonsillitis tissue

Positive FC detected in:
HepG2 cells, HEK-293 cells

Recommended dilution:
WB : 1:1000-1:8000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
major histocompatibility complex, class I, A

Calculated molecular weight:
41 kDa

Observed molecular weight:
44 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HLA-A

Synonyms
HLA A, HLA class I, HLA class I (HLA-A), HLA class I ABC, HLA-A, MHC class I antigen A*3
Background

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6 (6p21.3). There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D). This class I molecules are polymorphic membrane glycoproteins composed of a heavy (alpha) chain (44 kDa) which is encoded by a HLA class I gene (HLA-A, B or C), and β2-microglobulin light (beta) chain (12 kDa). They are involved in the presentation of foreign antigens to the immune system. (PMID: 667938; 3375250)


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