IDO1 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66528-1-Ig |CloneNo.: 3G2G11

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Freight/Packing

Con: 150 μg/150 μl

Choose size:

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Species specificity:
Human, mouse, rat

Positive WB detected in:
A431 cells,HSCT6 cells, 4T1 cells

Recommended dilution:
WB : 1:1000-1:10000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
indoleamine 2,3-dioxygenase 1

Calculated molecular weight:
403aa,45 kDa

Observed molecular weight:
42 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IDO1

Synonyms
CD107B, IDO, IDO 1, IDO1, INDO, indoleamine 2,3 dioxygenase 1
Background

IDO1 is the target for therapy in a range of clinical settings, including cancer, chronic infections, autoimmune and allergic syndromes, and transplantation. Elevated IDO1 expression is a hallmark of major viral infections including HIV, HBV, HCV or influenza and also of major bacteria infections, such as Tb, CAP, listeriosis and sepsis. Pathogens are able to highjack the immunosuppressive effects of IDO1 and make use of them to facilitate their own life cycle. MW of IDO1 is 40-42kd (PMID: 14502282; 17055065).


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