IL-4 Antibody 2 Publications

Mouse Monoclonal| Catalog number: 66142-1-Ig |CloneNo.: 1G2C5

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Freight/Packing

Con: 111 μg/150 μl

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Species specificity:
human, rat

Positive WB detected in:
Jurkat cells, Transfected HEK-293 cells

Positive IHC detected in:
human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 4

Calculated molecular weight:
153aa,17 kDa

Observed molecular weight:
18 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL4

Synonyms
B cell stimulatory factor 1, Binetrakin, BSF 1, BSF1, IL 4, IL4, IL-4, interleukin 4, PS1TP5BP1
Background

IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.


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