Cytokeratin 19 Antibody 1 Publications

Mouse Monoclonal| Catalog number: 60187-1-Ig |CloneNo.: 3G1E4

Featured Product KD/KO validated

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Freight/Packing

Con: 170 μg/150 μl

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Species specificity:
human

Positive WB detected in:
MCF-7 cells,HeLa cells, HepG2 cells

Positive IHC detected in:
human stomach cancer tissue,human lung cancer tissue, human breast cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
keratin 19

Calculated molecular weight:
44 kDa

Observed molecular weight:
48 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT19

Synonyms
CK 19, CK19, Cytokeratin 19, K19, K1CS, keratin 19, KRT19
Background

The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.


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