STAT1 Antibody 13 Publications

Rabbit Polyclonal| Catalog number: 10144-2-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 20 μg/150 μl

Choose size:

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Species specificity:
human, rat, mouse

Positive WB detected in:
PC-3 cells, multi-cells

Positive IP detected in:
PC-3 cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human testis tissue

Positive IF detected in:
PC-3 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
signal transducer and activator of transcription 1, 91kDa

Calculated molecular weight:
83 kDa

Observed molecular weight:
84 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
STAT1

Synonyms
DKFZp686B04100, ISGF 3, STAT1, STAT91
Background

STAT1 (signal transducers and activators of transcription 1) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Various ligands, including interferons- and - , EGF, PDGF and IL-6, can activate STAT1. STAT1 protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human STAT1.


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