CD117 (c-Kit) Monoklonaler Antikörper

CD117 (c-Kit) Monoklonal Antikörper für FC

Wirt / Isotyp

Ratte / IgG2b

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

ACK2

Kat-Nr. : PE-65094

Synonyme

Fdc, Gsfsco1, Gsfsco5, Gsfsow3, kit oncogene, SCO1, SCO5, SOW3, Ssm, Tr kit



Geprüfte Anwendungen

Erfolgreiche Detektion in FCMaus-Knochenmarkzellen

Empfohlene Verdünnung

AnwendungVerdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-65094 bindet in FC CD117 (c-Kit) und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Ratte / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen Murine IL-3-abhängige Mastzellen
Vollständiger Name kit oncogene
GenBank-ZugangsnummerBC052457
Gene symbol Kit
Gene ID (NCBI) 16590
Konjugation PE Fluorescent Dye
Excitation/Emission maxima wavelengths496 nm, 565 nm / 578 nm
Form Liquid
Reinigungsmethode Affinitätsreinigung
Lagerungspuffer Phosphatbasierter Puffer mit 0,09% Natriumazid und 0,1% Gelatine, pH 7,2.
LagerungsbedingungenBei 2-8°C lagern. Vor Licht schützen. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD117, also known as c-Kit and SCFR, is a transmembrane protein with tyrosine kinase activity encoded by the oncogene c-kit (PMID: 2448137). It is a member of the type III receptor tyrosine kinase family, which also includes CSF-1R, PDGFRβ, PDGFRα, and FLT3 (PMID: 29518044). CD117 is expressed on hematopoietic stem cells and progenitor cells, mast cells, and is also found in a wide range of non-haemopoietic cell types (including melanocytes, germ cells, astrocytes, renal tubules, breast glandular epithelial cells, sweat glands, and interstitial cells of Cajal) (PMID: 10582338; 23073628). CD117 plays an important role in early haemopoiesis. It is also involved in pigmentation, fertility, gut movement, and some aspects of the nervous system (PMID: 23073628).

Protokolle

Produktspezifische Protokolle
FC protocol for PE CD117 (c-Kit) antibody PE-65094Protokoll herunterladen
Standard-Protokolle
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