Anticorps Polyclonal de lapin anti-EEA1

EEA1 Polyclonal Antibody for ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

ELISA

Conjugaison

Non conjugué

Publications(8)

N° de cat : 22266-1-AP

Synonymes

EEA1

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Galerie de données de validation

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  WB analysis of NIH/3T3 using 22266-1-AP

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 22266-1-AP (EEA1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Informations sur le produit

22266-1-AP cible EEA1 dans les applications de ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: early endosome antigen 1
• Masse moléculaire calculée: 162 kDa
• Numéro d’acquisition GenBank: NM_003566
• Symbole du gène: EEA1
• Identification du gène (NCBI): 8411
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Early endosome antigen 1 (EEA1) is a marker of early endosomes and has an important role in endosomal trafficking. EEA1 contains coiled-coil regions and an FYVE-type zinc finger which interacts with phosphatidylinositol-3-phosphate. EEA1 functions as a Rab5 effector, mediates endosome docking and, together with SNAREs, leads to membrane fusion.

Publications

Species	Application	Title
		Immunity; The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.; Authors - Meihong Deng
human		EMBO J; FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.; Authors - Wenxian Wu
		Br J Pharmacol; An orally available hypoglycaemic peptide taken up by caveolae transcytosis displays improved hypoglycaemic effects and body weight control in db/db mice.; Authors - Weisheng Lu
		Int J Cancer; TGF-β induced PAR-1 expression promotes tumor progression and osteoclast differentiation in giant cell tumor of bone.; Authors - Ting Wang
human		J Exp Clin Cancer Res; Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation.; Authors - Minghui Chang
human		Virol J; A GFP-tagged version of the pseudorabies virus protein UL56 localizes to the Golgi and trans-Golgi network through a predicted C-terminal leucine-rich helix in transfected cells.; Authors - Chuang Lyu

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