ABI3 Polyclonal antibody, PBS Only

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• ABI3 Polyclonal antibody, PBS Only (16227-1-PBS)

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  WB analysis using 16227-1-AP (same clone as 16227-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16227-1-AP (ABI3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16227-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 16227-1-AP (same clone as 16227-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 16227-1-AP (ABI3 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16227-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 16227-1-AP (same clone as 16227-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 16227-1-AP (ABI3 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16227-1-PBS in a different storage buffer formulation.

ABI3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 16227-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

SSH3BP3, New molecule including SH3, Nesh, ABI gene family member 3, ABI family, member 3

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Product Information

16227-1-PBS targets ABI3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag8164

  Product name: Recombinant human ABI3 protein

  Source: e coli.-derived, PET28a

  Tag: 6*His

  Domain: 1-366 aa of BC007780

  Sequence: MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPPGQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC

• Full Name: ABI family, member 3
• Calculated Molecular Weight: 366 aa, 39 kDa
• Observed Molecular Weight: 50 kDa
• GenBank Accession Number: BC007780
• Gene Symbol: ABI3
• Gene ID (NCBI): 51225
• RRID: AB_3741879
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9P2A4
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ABI family member 3 belongs to the ABL Interactors (ABI) family of proteins, which also includes ABI1 and ABI2. ABI proteins are a class of cytoplasmic molecular junction proteins originally identified as binding chaperones for Abl kinase. The ABI3 gene is thought to be an important regulator of microglia during Alzheimer's disease (AD), and its S209F variant increases the risk of developing AD. Moreover, ABI3 plays an important role in suppressing tumor growth and progression.