ACSL6 Polyclonal antibody, PBS Only

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• ACSL6 Polyclonal antibody, PBS Only (13847-1-PBS)

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  WB analysis using 13847-1-AP (same clone as 13847-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13847-1-AP (ACSL6 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 13847-1-AP (same clone as 13847-1-PBS)

  IP result of anti-ACSL6 (IP:13847-1-AP, 4ug; Detection:13847-1-AP 1:2000) with mouse brain tissue lysate 2120 ug. This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

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  IHC staining of human urothelial carcinoma using 13847-1-AP (same clone as 13847-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 13847-1-AP (ACSL6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas cancer using 13847-1-AP (same clone as 13847-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 13847-1-AP (ACSL6 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13847-1-PBS in a different storage buffer formulation.

ACSL6 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Cat No. 13847-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, IP, Indirect ELISA

Synonyms

ACSL 6, Arachidonate--CoA ligase, EC:6.2.1.15, EC:6.2.1.3, FACL6

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Product Information

13847-1-PBS targets ACSL6 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag4817

  Product name: Recombinant human ACSL6 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 48-349 aa of BC047453

  Sequence: THYYDDARTMYQVFRRGLSISGNGPCLGFRKPKQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQANHQAPVPPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTEGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASL

• Full Name: acyl-CoA synthetase long-chain family member 6
• Calculated Molecular Weight: 78 kDa
• Observed Molecular Weight: 74 kDa
• GenBank Accession Number: BC047453
• Gene Symbol: ACSL6
• Gene ID (NCBI): 23305
• RRID: AB_3741844
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9UKU0
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ACSL6 (Acyl-CoA Synthetase Long Chain Family Member 6) is a long-chain lipoyl-coenzyme A synthetase that is mainly responsible for catalyzing the binding of long-chain fatty acids to coenzyme A to form acyl-coenzyme A (Acyl-CoA). ACSL6 is involved in fatty acid metabolic transporter and the synthesis of cell membrane phospholipids, which affects the cell structure and function. ACSL6 plays an extremely important role in the pathogenesis of cancers such as hepatocellular carcinoma, lung cancer and neuroblastoma, suggesting that it may serve as a biomarker and therapeutic target for cancer therapy.