CoraLite®594-conjugated ARL13B Monoclonal antibody

ARL13B Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2a

Reactivity

Human, Canine

Applications

IF

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

1H6C3

Cat no : CL594-66739

Synonyms

ARL13B, ARL2 like protein 1, ARL2L1, DKFZp686E2075, DKFZp686L2472, DKFZp686M2074, DKFZp761H079, JBTS8



Tested Applications

Positive IF detected inMDCK cells
For other applications, we recommend the unconjugated version of this antibody, 66739-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

CL594-66739 targets ARL13B in IF applications and shows reactivity with Human, Canine samples.

Tested Reactivity Human, Canine
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen ARL13B fusion protein Ag12031
Full Name ADP-ribosylation factor-like 13B
Calculated molecular weight 48 kDa
Observed molecular weight 60 kDa
GenBank accession numberBC094725
Gene symbol ARL13B
Gene ID (NCBI) 200894
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths593 nm/614 nm
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).

Protocols

Product Specific Protocols
IF protocol for CL594 ARL13B antibody CL594-66739Download protocol
Standard Protocols
Click here to view our Standard Protocols