ASNA1 Monoclonal antibody, PBS Only
ASNA1 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat, pig, chicken
Applications
WB, IHC, IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1B7C11
Cat no : 66346-1-PBS
Synonyms
Validation Data Gallery
Product Information
66346-1-PBS targets ASNA1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, chicken samples.
Tested Reactivity | human, mouse, rat, pig, chicken |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | ASNA1 fusion protein Ag7936 |
Full Name | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) |
Calculated Molecular Weight | 38.7 kDa |
Observed Molecular Weight | 37-41 kDa |
GenBank Accession Number | BC002651 |
Gene Symbol | ASNA1 |
Gene ID (NCBI) | 439 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth, increased apoptosis and increased sensitivity to arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition, ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.