Calbindin-D28k Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 14479-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, human brain tissue, human kidney tissue, rat brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human cerebellum tissue, human brain tissue, human cerebellum tissue, human kidney tissue, human small intestine tissue

Positive IF detected in:
mouse cerebellum tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
calbindin 1, 28kDa

Calculated molecular weight:
30 kDa

Observed molecular weight:
28 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CALB1

Synonyms
CAB27, CALB, CALB1, Calbindin, calbindin 1, 28kDa, Calbindin D28, D 28K
Background

Calbindin-D28k is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. It is a cytosolic calcium binding protein highly expressed in the distal tubule, intestines, central nervous system, primary murine osteoblast cells and in several other organs. It plays an important role in the intracellular calcium homeostasis, its strong buffering capacity prevents cytotoxic effect of high concentration of free calcium in kidney, brain, pancreas, and intestine.


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