CCBL2 Polyclonal antibody, PBS Only

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• CCBL2 Polyclonal antibody, PBS Only (55476-1-PBS)

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  WB analysis using 55476-1-AP (same clone as 55476-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55476-1-AP (CCBL2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55476-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 55476-1-AP (same clone as 55476-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 55476-1-AP (CCBL2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55476-1-PBS in a different storage buffer formulation.

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  IF Staining of K-562 using 55476-1-AP (same clone as 55476-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed K-562 cells using CCBL2 antibody (55476-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 55476-1-PBS in a different storage buffer formulation.

CCBL2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Cat No. 55476-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Synonyms

Glutamine Transaminase L, GTL, KAT3, KATIII, RBMXL1

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Product Information

55476-1-PBS targets CCBL2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: cysteine conjugate-beta lyase 2
• Calculated Molecular Weight: 51 kDa
• Observed Molecular Weight: 48 kDa，51- 55 kda
• GenBank Accession Number: NM_019610
• Gene Symbol: CCBL2
• Gene ID (NCBI): 56267
• RRID: AB_3670254
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q6YP21
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Cysteine conjugate beta-lyase 2 (CCBL2), also known as kynurenine aminotransferase 3 (KAT3) or glutamine transaminase L (GTL), can effectively catalyze the transamination of glutamine, methionine, and kynurenine (KYN) to kynurenic acid (KYNA) as well as the pathway of drug metabolism by cytochrome P450. CCBL2 has been found in mouse, rat, and human whose mRNA is widely expressed in several organs such as the liver, kidney, heart, and neuroendocrine tissues (PMID: 35771747).