CCR3 Recombinant antibody, PBS Only

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  WB analysis using 86038-1-RR (same clone as 86038-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86038-1-RR (CCR3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86038-1-PBS in a different storage buffer formulation.

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  IF Staining of K-562 using 86038-1-RR (same clone as 86038-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed K-562 cells using CCR3 antibody (86038-1-RR, Clone: 250209D5 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 86038-1-PBS in a different storage buffer formulation.

CCR3 Uni-rAb^TM Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 86038-1-PBS

Clone No.250209D5

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

C C chemokine receptor type 3, C C CKR 3, C C CKR3, C-C chemokine receptor type 3, CC CKR 3

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Product Information

86038-1-PBS targets CCR3 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Peptide
• Full Name: chemokine (C-C motif) receptor 3
• Calculated Molecular Weight: 355 aa, 41 kDa
• Observed Molecular Weight: 53 kDa
• GenBank Accession Number: BC110297
• Gene Symbol: CCR3
• Gene ID (NCBI): 1232
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P51677
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CCR3 (C-C Motif Chemokine Receptor 3), also known as CD193, is a G protein-coupled receptor (GPCR) primarily involved in immune cell trafficking and inflammation regulation and highly expressed in eosinophils and basophils, with detectable levels in Th2 cells, airway epithelial cells, and subsets of monocyte-derived dendritic cells (PMID: 21077277). Ligand-induced CCR3 internalization is required for eosinophil shape change and actin polymerization but not for calcium mobilization or desensitization (PMID: 12532103).