PE Anti-Mouse CD103 (2E7)
CD103 Monoclonal Antibody for FC
Host / Isotype
Hamster / IgG
Reactivity
Mouse
Applications
FC
Conjugate
PE Fluorescent Dye
CloneNo.
2E7
Cat no : PE-65047
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | mouse splenocytes |
Recommended dilution
Application | Dilution |
---|---|
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
PE-65047 targets CD103 in FC applications and shows reactivity with Mouse samples.
Tested Reactivity | Mouse |
Host / Isotype | Hamster / IgG |
Class | Monoclonal |
Type | Antibody |
Immunogen | C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL) |
Full Name | integrin alpha E, epithelial-associated |
GenBank Accession Number | BC150690 |
Gene Symbol | Itgae |
Gene ID (NCBI) | 16407 |
RRID | AB_2883847 |
Conjugate | PE Fluorescent Dye |
Excitation/Emission Maxima Wavelengths | 496 nm, 565 nm / 578 nm |
Form | Liquid |
Purification Method | Affinity purification |
Storage Buffer | PBS with 0.1% sodium azide and 0.5% BSA. |
Storage Conditions | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Background Information
CD103, also known as integrin alpha-E (ITGAE) or integrin alpha-IEL, is a type I transmembrane integrin protein that binds integrin beta 7 to form Integrin alpha-E beta-7 which is a receptor for E-cadherin and mediates adhesion of T lymphocytes to epithelial cells (PMID: 7969453; 8468482). CD103 is expressed on intraepithelial lymphocyte (IEL) T cells (both alpha/beta T cells and gamma/delta T cells), some peripheral regulatory T cells (Tregs), lamina propria T cells, and a subset of dendritic cells in the gut mucosa and mesenteric lymph nodes (PMID: 12242333; 15608520; 16216890).
Protocols
Product Specific Protocols | |
---|---|
FC protocol for PE CD103 antibody PE-65047 | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |