Anti-Mouse CD16/CD32 (93), PBS Only

CD16/CD32 Monoclonal Antibody for FC
Cat No. 65057-1-PBS
Clone No.93

Host / Isotype

Rat / IgG2a, lambda

Reactivity

mouse

Applications

CD16/32, CD32, 93, Fc gamma receptor IIB, Fc-gamma RII

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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65057-1-Ig

Product Information

65057-1-PBS targets CD16/CD32 in applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rat / IgG2a, lambda
Class Monoclonal
Type Antibody
Immunogen VH81X Tg B cells and T220 stromal cell line Predict reactive species
Full Name Fc receptor, IgG, low affinity IIb
GenBank Accession NumberBC038070
Gene Symbol CD16/32
Gene ID (NCBI) 14130
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP08101
Storage Buffer PBS Only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

CD16 (FcγRIII) is a 50-70 kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD32 (FcγRII) is a 40 kD transmembrane glycoprotein that binds to the Fc region of IgG with low affinity. CD32 is present on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Rat anti mouse CD16/32 antibody, clone 93 is specific to the common epitope of CD16 and CD32. It can be used for blocking non-specific binding of immunoglobulins to the Fc receptors by preincubating the cells with the purified antibody at 1 ug per million cells in 100 uL volume for 5-10 minutes prior to immunostaining.

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