Anti-Mouse CD44 (IM7)

CD44 Monoclonal Antibody for FC

Host / Isotype

Rat / IgG2b

Reactivity

Human, Mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

IM7

Cat no : 65117-1-Ig

Synonyms

CD44, CD44 antigen, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP 1, PGP I, Pgp1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I



Tested Applications

Positive FC detected inmouse splenocytes

Recommended dilution

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

65117-1-Ig targets CD44 in FC applications and shows reactivity with Human, Mouse samples.

Tested Reactivity Human, Mouse
Host / Isotype Rat / IgG2b
Class Monoclonal
Type Antibody
Immunogen Dexamethasone-induced myeloid leukemia M1 cells
Full Name CD44 antigen
GenBank accession numberBC051388
Gene symbol Cd44
Gene ID (NCBI) 12505
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer Phosphate based buffer with 0.09% sodium azide, pH 7.2.
Storage ConditionsStore at 2-8°C.

Background Information

CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.

Protocols

Product Specific Protocols
FC protocol for CD44 antibody 65117-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols