CoraLite® Plus 488 Anti-Mouse CD44 (IM7)
CD44 Monoclonal Antibody for FC, IF
Host / Isotype
Rat / IgG2b, kappa
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-65117
|Positive IF detected in
|Positive FC detected in
|IF : 1:50-1:500
|This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 µl per 10^6 cells in a 100 µl suspension or 5 µl per 100 µl of whole blood.
|Sample-dependent, check data in validation data gallery
CL488-65117 targets CD44 in IF, FC applications and shows reactivity with Human, Mouse samples.
|Host / Isotype
|Rat / IgG2b, kappa
|Dexamethasone-induced myeloid leukemia M1 cells
|GenBank accession number
|Gene ID (NCBI)
|CoraLite® Plus 488 Fluorescent Dye
|Excitation/Emission maxima wavelengths
|493 nm / 522 nm
|PBS with 0.1% sodium azide and 0.5% BSA, pH 7.3.
|Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.