|Positive IF detected in||Jurkat cells|
|Positive FC detected in||human peripheral blood lymphocytes|
|Immunofluorescence (IF)||IF : 1:2500-1:10000|
|This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.|
|Sample-dependent, check data in validation data gallery|
65109-1-Ig targets CD45 in IF, FC applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Human peripheral blood leucocytes|
|Full Name||protein tyrosine phosphatase, receptor type, C|
|GenBank accession number||BC014239|
|Gene ID (NCBI)||5788|
|Purification Method||Affinity purification|
|Storage Buffer||Phosphate based buffer with 0.09% sodium azide, pH 7.2.|
|Storage Conditions||Store at 2-8°C. Stable for one year after shipment.|
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097).