|Positive FC detected in||human PBMCs|
|This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.|
|Sample-dependent, check data in validation data gallery|
PE-65109 targets CD45 in FC applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Human peripheral blood leucocytes|
|Full Name||protein tyrosine phosphatase, receptor type, C|
|GenBank accession number||BC014239|
|Gene ID (NCBI)||5788|
|Conjugate||PE Fluorescent Dye|
|Excitation/Emission maxima wavelengths||496 nm, 565 nm / 578 nm|
|Purification Method||Affinity purification|
|Storage Buffer||PBS with 0.09% sodium azide and 0.5% BSA.|
|Storage Conditions||Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.|
CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097).