Anti-Human CD62L (DREG56)
CD62L Monoclonal Antibody for FC
Host / Isotype
Mouse / Mouse IgG1
Reactivity
Human
Applications
FC
Conjugate
Unconjugated
CloneNo.
DREG56
Cat no : 65167-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | human peripheral blood lymphocytes |
Recommended dilution
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Product Information
65167-1-Ig targets CD62L in FC applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / Mouse IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | PMA-activated human peripheral blood leukocytes |
Full Name | selectin L |
Calculated molecular weight | 42 kDa |
GenBank accession number | BC020758 |
Gene symbol | SELL |
Gene ID (NCBI) | 6402 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Purified by protein-A affinity chromatography |
Storage Buffer | PBS with 0.1% sodium azide. |
Storage Conditions | Store at 2-8°C. |
Background Information
CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078).
Protocols
Product Specific Protocols | |
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FC protocol for CD62L antibody 65167-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |