CDK4 Monoclonal antibody, PBS Only
CDK4 Monoclonal Antibody for WB, FC, IHC, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, Mouse, Rat
Applications
WB, FC, IHC, ELISA
Conjugate
Unconjugated
CloneNo.
1G2C12
Cat no : 66950-1-PBS
Synonyms
Validation Data Gallery
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
66950-1-PBS targets CDK4 in WB, FC, IHC, ELISA applications and shows reactivity with Human, Mouse, Rat samples.
Tested Reactivity | Human, Mouse, Rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | CDK4 fusion protein Ag20538 |
Full Name | cyclin-dependent kinase 4 |
Calculated Molecular Weight | 34 kDa |
Observed Molecular Weight | 34 kDa |
GenBank Accession Number | BC010153 |
Gene Symbol | CDK4 |
Gene ID (NCBI) | 1019 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS only |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. It is essential for the G1- to S-phase transition during the cell cycle and its expression is primarily controlled at the transcriptional level(PMID:17253961). CCND1-CDK4 axis is not only critical in glial tumor cells but also in stromal-derived cells in the surrounding tumor microenvironment that are vital to sustain tumor outgrowth(PMID:21844184).