Product Information
32922-1-PBS targets CFAP221 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag38512 Product name: Recombinant human hCG_17324 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 265-508 aa of NM_001271049.1 Sequence: LEEFERLNTLSKKVNVPPEKAMMHINFHRPPAKPKPQKVKEIEYQNLRFPVDLSNPFAVATVLNQEPGKLKIKELREVLDQGTEISKTRQMKEALFEQKVRQDIHEEMENHLKWQVHLGKDPMSFKLKKELTEEWQKACAKYKLDRGDPILDEEFQRLKTEVSHKRVVRNQEEKIKEFHPTFDPLINNTWLSRSRAQKRFQQVARKVMIQGRLFNMLSAVREMDKESILRKIGQAKQSIAQEAN Predict reactive species |
| Full Name | primary ciliary dyskinesia protein 1 |
| Calculated Molecular Weight | 97kDa，840a |
| Observed Molecular Weight | 100 kDa |
| GenBank Accession Number | NM_001271049.1 |
| Gene Symbol | hCG_17324 |
| Gene ID (NCBI) | 200373 |
| RRID | AB_3742788 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q4G0U5 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
CFAP221 (also known as PCDP1) is a crucial structural protein in motile cilia and sperm flagella. It is specifically located within the axillary shaft of the cilia and acts as a "connection bridge" between the adjacent outer doublet microtubules, playing a role in stabilizing the core skeleton of the axillary shaft and coordinating the sliding of microtubules. The loss of this protein's function will disrupt the structural integrity and normal oscillation of the cilia, leading to a genetic disorder known as primary ciliary dyskinesia.
