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CISD2-Specific Monoclonal antibody, PBS Only

CISD2-Specific Monoclonal Antibody for WB, IF, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2b


human, zebrafish, rat, mouse


WB, IF, IHC, Indirect ELISA





Cat no : 66082-1-PBS


CDGSH iron sulfur domain 2, CDGSH2, CISD2, CISD2-Specific, ERIS, Miner1, MitoNEET related 1 protein, NAF 1, WFS2, ZCD2

Recommended dilution

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66082-1-PBS targets CISD2-Specific in WB, IF, IHC, Indirect ELISA applications and shows reactivity with human, zebrafish, rat, mouse samples.

Tested Reactivity human, zebrafish, rat, mouse
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen Recombinant protein
Full Name CDGSH iron sulfur domain 2
Observed Molecular Weight 15 kDa
GenBank Accession NumberNM_001008388
Gene Symbol CISD2
Gene ID (NCBI) 493856
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

CISD2 gene encodes a 15 kDa CDGSH iron-sulfur domain-containing protein 2, which is also named Miner1 or NAF-1, this protein was reported on endoplasmic reticulum membrane or mitochondrion outer membrane. Defects in CISD2 are the cause of Wolfram syndrome type 2 (WFS2), a rare disorder characterized by juvenile-onset insulin-dependent diabetes mellitus with optic atrophy. CISD2 regulates autophagy program by interacting BCL2, contributing to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. This monoclonal antibody is specific to CISD2 and does not cross-react with CISD1.