Mouse CLEC10A/CD301 Recombinant monoclonal antibody, PBS Only

• 

  WB analysis of RAW 264.7 using 85911-5-RR (same clone as 85911-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85911-5-RR (CLEC10A/CD301 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85911-5-PBS in a different storage buffer formulation.

CLEC10A/CD301 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 85911-5-PBS

Clone No.242636A8

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, Indirect ELISA

Synonyms

Clec10a, C-type lectin domain family 10 member A, Macrophage asialoglycoprotein-binding protein 1, Macrophage galactose/N-acetylgalactosamine-specific lectin, M-ASGP-BP-1

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Product Information

85911-5-PBS targets CLEC10A/CD301 in WB, Indirect ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg2698

  Product name: Recombinant Mouse MGL1/CD301a protein (rFc Tag) (HPLC verified)

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 57-304 aa of NM_010796.3

  Sequence: QNSQLRRDLGTLRATLDNTTSKIKAEFQSLDSRADSFEKGISSLKVDVEDHRQELQAGRDLSQKVTSLESTVEKREQALKTDLSDLTDHVQQLRKDLKALTCQLANLKNNGSEVACCPLHWTEHEGSCYWFSESEKSWPEADKYCRLENSHLVVVNSLEEQNFLQNRLANVVSWIGLTDQNGPWRWVDGTDFEKGFKNWAPLQPDNWFGHGLGGGEDCAHITTGGPWNDDVCQRTFRWICEMKLAKES

• Full Name: macrophage galactose N-acetyl-galactosamine specific lectin 1
• Calculated Molecular Weight: 35 kDa
• Observed Molecular Weight: 40 kDa
• GenBank Accession Number: NM_010796.3
• Gene Symbol: Mgl1
• Gene ID (NCBI): 17312
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P49300
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

C-type lectin domain family 10 member A (CLEC10A), also known as CD301, macrophage galactose-type C-type lectin (MGL), DC-asialoglyco protein receptor (DC-ASGP-R) or human macrophage lectin (HML), is a type II transmembrane glycoprotein having a calcium-dependent carbohydrate recognition domain (PMID: 8598452; 11919201; 11698450). CLEC10A is expressed exclusively by myeloid professional antigen-presenting cells such as immature dendritic cells (DCs) and alternatively activated macrophages (PMID: 16998493). CLEC10A is a marker for human CD1c+ DCs (cDC2) (PMID: 29755453). It functions as an endocytic receptor for glycosylated antigens (PMID: 11919201).