CLTC Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66487-1-Ig |CloneNo.: 1B3D7

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Con: 150 μg/150 μl

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Species specificity:
Human, Pig, Mouse, Rat

Positive WB detected in:
HeLa cells, Raji cells

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:20000-1:80000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
clathrin, heavy chain (Hc)

Calculated molecular weight:
192 kDa

Observed molecular weight:
170 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CLTC

Synonyms
CHC, CHC17, Clathrin heavy chain 1, clathrin, heavy chain (Hc), CLH 17, CLH17, CLTC, CLTCL2, Hc, KIAA0034
Background

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. The clathrin molecule has a triskelion shape. Each clathrin triskelion is composed of three identical heavy chains (CLTC) (160-190 kDa) and three light chains of two types, LCA (CLTA) and LCB (CLTB) (30-40 kDa). The heavy chain provides the structural backbone of the clathrin lattice. (PMID: 9133677)


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