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Collagen Type III (C-terminal) Polyclonal antibody
Collagen Type III (C-terminal) Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat, pig
WB, IHC, IF, ELISA
Cat no : 13548-1-AP
|Positive IHC detected in||human hepatocirrhosis tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 1 publications below|
|WB||See 37 publications below|
|IHC||See 5 publications below|
|IF||See 4 publications below|
13548-1-AP targets Collagen Type III (C-terminal) in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat, pig samples.
|Tested Reactivity||human, mouse, rat, pig|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Collagen Type III (C-terminal) fusion protein Ag4229|
|Full Name||collagen, type III, alpha 1|
|Calculated molecular weight||1466 aa, 139 kDa|
|Observed molecular weight||140 kDa|
|GenBank accession number||BC028178|
|Gene ID (NCBI)||1281|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Type III collagen is a fibrillar forming collagen comprising three a1(III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. It occurs in most soft connective tissues along with type I collagen. COL3A1 gene encodes type III procollagen. Mutations in this gene are associated with type III and IV Ehlers-Danlos syndrome, and with aortic and arterial aneurysms. (PMID: 9050868; 2445760)
|Product Specific Protocols|
|IHC protocol for Collagen Type III (C-terminal) antibody 13548-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.
Epithelial but not stromal expression of collagen alpha-1(III) is a diagnostic and prognostic indicator of colorectal carcinoma.
Cell Death Dis
Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling.
J Mol Cell Cardiol
Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.
Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways.
Cell Death Dis
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis.