COMP Monoclonal antibody

COMP Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, pig

Applications

WB,ELISA

Conjugate

Unconjugated

CloneNo.

1D7A6

Cat no : 66793-1-Ig

Synonyms

COMP, EDM1, EPD1, MED, PSACH, THBS5, Thrombospondin 5, TSP5



Tested Applications

Positive WB detected inpig cartilage tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Sample-dependent, check data in validation data gallery

Product Information

66793-1-Ig targets COMP in WB,ELISA applications and shows reactivity with Human, pig samples.

Tested Reactivity Human, pig
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen COMP fusion protein Ag4575
Full Name cartilage oligomeric matrix protein
Calculated molecular weight 757 aa, 83 kDa
Observed molecular weight 100-130 kDa
GenBank accession numberBC033676
Gene symbol COMP
Gene ID (NCBI) 1311
Conjugate Unconjugated
Form Liquid
Purification Method Protein G purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

COMP is a secreted pentameric glycoprotein built from modular units and belongs to the thrombospondin protein family. COMP is expressed by hypertrophic chondrocytes and osteoblasts during endochondral ossification, and its expression is increased during fracture healing. COMP is involved in the assembly of collagen fibrils and other structural matrix components. COMP interacts with a number of cartilage ECM proteins, including fibronectin, collagen I, II IX, XII, and XIV, matrilins, as well as proteoglycans such as aggrecan and others. This antibody got 100-130 kDa maybe due to glycosylation.

Protocols

Product Specific Protocols
WB protocol for COMP antibody 66793-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols