Product Information
33924-1-PBS targets Calpain 15/SOLH in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag40689 Product name: Recombinant human SOLH protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-150 aa of BC021854 Sequence: MATVGEWSCVRCTFLNPAGQRQCSICEAPRHKPDLNHILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPAPGAAFLPVLNGVLPKPPAILGEPKGSCQEEAGPVRTAGLVATEPARGQCEDKDEEEKEEQEEEEGAAEPRGGWACP Predict reactive species |
| Full Name | small optic lobes homolog (Drosophila) |
| Calculated Molecular Weight | 117 kDa |
| Observed Molecular Weight | 117 kDa |
| GenBank Accession Number | BC021854 |
| Gene Symbol | SOLH |
| Gene ID (NCBI) | 6650 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | O75808 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
Calpain 15 (also known as CAPN15 and SOLH) is an intracellular cysteine protease belonging to the non-classical small optic lobe (SOL) family of calpains, which plays an important role in developmental processes (PMID: 40238785). Capn15 is expressed at much higher levels during early neuronal development than in the adult (PMID: 32885237). And loss of Capn15 in forebrain excitatory neurons leads to some behavioral deficits including decreased fear generalization (PMID: 37598906).
