Caspase 2/p32/p18 Monoclonal antibody

Caspase 2/p32/p18 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

2G4C2

Cat no : 66517-1-Ig

Synonyms

CASP 2, CASP2, Caspase 2, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1



Tested Applications

Positive WB detected inJurkat cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Sample-dependent, check data in validation data gallery

Product Information

66517-1-Ig targets Caspase 2/p32/p18 in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Caspase 2/p32/p18 fusion protein Ag20141
Full Name caspase 2, apoptosis-related cysteine peptidase
Calculated molecular weight 452 aa, 51 kDa
Observed molecular weight 51 kDa, 32 kDa, 18 kDa
GenBank accession numberBC002427
Gene symbol CASP2
Gene ID (NCBI) 835
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

Protocols

Product Specific Protocols
WB protocol for Caspase 2/p32/p18 antibody 66517-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols