CoraLite® Plus 488-conjugated Caspase 2/p32/p18 Monoclonal antibody

Caspase 2/p32/p18 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG1






CoraLite® Plus 488 Fluorescent Dye



Cat no : CL488-66517


CASP 2, CASP2, Caspase 2, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1

Tested Applications

Positive IF detected inHeLa cells

Recommended dilution

Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

CL488-66517 targets Caspase 2/p32/p18 in IF applications and shows reactivity with Human samples.

Tested Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Caspase 2/p32/p18 fusion protein Ag20141
Full Name caspase 2, apoptosis-related cysteine peptidase
Calculated Molecular Weight 452 aa, 51 kDa
Observed Molecular Weight48-51 kDa, 32 kDa, 18 kDa
GenBank Accession NumberBC002427
Gene Symbol CASP2
Gene ID (NCBI) 835
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission Maxima Wavelengths493 nm / 522 nm
Form Liquid
Purification MethodProtein G purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.


Product Specific Protocols
IF protocol for CL Plus 488 Caspase 2/p32/p18 antibody CL488-66517Download protocol
Standard Protocols
Click here to view our Standard Protocols