Cleaved Caspase 4/P20 Recombinant monoclonal antibody, PBS Only

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  WB analysis using 85770-1-RR (same clone as 85770-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85770-1-RR (Cleaved Caspase 4/P20 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85770-1-PBS in a different storage buffer formulation.

Cleaved Caspase 4/P20 Uni-rAb^® Recombinant Antibody for WB, Indirect ELISA

Cat No. 85770-1-PBS

Clone No.243150D6

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

CASP4, Caspase4, CASP 4, CASP-4, Caspase 4

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Product Information

85770-1-PBS targets Cleaved Caspase 4/P20 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: caspase 4, apoptosis-related cysteine peptidase
• Calculated Molecular Weight: 377 aa, 43 kDa
• Observed Molecular Weight: 20 kDa
• GenBank Accession Number: BC017839
• Gene Symbol: Caspase 4
• Gene ID (NCBI): 837
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P49662
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Caspase-4 participates in cleavage and activates gasdermin D (GSDMD), leading to cell membrane perforation, cell swelling and rupture, thereby inducing pyroptosis.