DR3 Polyclonal antibody, PBS Only

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• DR3 Polyclonal antibody, PBS Only (55397-1-PBS)

• 

  WB analysis of PC-3 using 55397-1-AP (same clone as 55397-1-PBS)

  WB result of DR3 antibody (55397-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-DR3 transfected PC-3 cells. This data was developed using the same antibody clone with 55397-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 55397-1-AP (same clone as 55397-1-PBS)

  PC-3 cells were subjected to SDS PAGE followed by western blot with 55397-1-AP (DR3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55397-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse spleen using 55397-1-AP (same clone as 55397-1-PBS)

  mouse spleen tissue were subjected to SDS PAGE followed by western blot with 55397-1-AP (DR3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55397-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse thymus using 55397-1-AP (same clone as 55397-1-PBS)

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 55397-1-AP (DR3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55397-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

DR3 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 55397-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

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Product Information

55397-1-PBS targets DR3 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: tumor necrosis factor receptor superfamily, member 25
• Calculated Molecular Weight: 46 kDa
• Observed Molecular Weight: 52 kDa, 17-20 kDa
• GenBank Accession Number: NM_003790
• Gene Symbol: DR3
• Gene ID (NCBI): 8718
• RRID: AB_11183036
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q93038
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TNFRSF25, also named as APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, LARD, TRAMP and AIR, is a receptor for TNFSF12/APO3L/TWEAK. TNFRSF25 interacts directly with the adapter TRADD. It mediates activation of NF-kappa-B and induces apoptosis. TNFRSF25 may play a role in regulating lymphocyte homeostasis. It is constitutively and highly expressed by CD4(+)FoxP3(+) Tregs. This antibody can recognize all the isoform of TNFRSF25.