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CoraLite® Plus 488-conjugated EPCAM Polyclonal antibody
EPCAM Polyclonal Antibody for FC
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
FC
Conjugate
CoraLite® Plus 488 Fluorescent Dye
Cat no : CL488-21050
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | MCF-7 cells, HT-29 cells |
Recommended dilution
Application | Dilution |
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Sample-dependent, check data in validation data gallery |
Product Information
CL488-21050 targets EPCAM in FC applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | EPCAM fusion protein Ag15393 |
Full Name | epithelial cell adhesion molecule |
Calculated molecular weight | 314 aa, 35 kDa |
Observed molecular weight | 35-40 kDa |
GenBank accession number | BC014785 |
Gene symbol | EPCAM |
Gene ID (NCBI) | 4072 |
Conjugate | CoraLite® Plus 488 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 493 nm / 522 nm |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Epithelial cell adhesion molecule (EpCAM, CD326) is a type I transmembrane glycoprotein that functions as a homophilic, epithelial-specific intercellular cell-adhesion molecule. In addition to cell adhesion, EpCAM is also involved in cellular signaling, cell migration, proliferation, and differentiation. EpCAM is highly expressed on most carcinomas and therefore of potential use as a diagnostic and prognostic marker for a variety of carcinomas, and has become a therapeutic target. EpCAM may occur in distinct forms due to glycosylation. (PMID: 20837599; 19249674; 21576002; 22647938; 12691820)
Protocols
Product Specific Protocols | |
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FC protocol for CL Plus 488 EPCAM antibody CL488-21050 | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |