|Positive WB detected in||human brain tissue, pig brain tissue, rat brain tissue, mouse cerebellum tissue|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Sample-dependent, check data in validation data gallery|
66667-1-Ig targets EPHA7 in WB, ELISA applications and shows reactivity with Human, Mouse, Rat, Pig samples.
|Tested Reactivity||Human, Mouse, Rat, Pig|
|Host / Isotype||Mouse / IgG1|
|Immunogen||EPHA7 fusion protein Ag3813|
|Full Name||EPH receptor A7|
|Calculated molecular weight||998 aa, 112 kDa|
|Observed molecular weight||120 kDa|
|GenBank accession number||BC027940|
|Gene ID (NCBI)||2045|
|Purification Method||Protein G purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Ephrin receptor A7 (EphA7) is a member of the Eph receptor family. EPHA7 plays a role in corticogenesis processes, determines brain size and shape, and is involved in development of the central nervous system (PMID:34176129). In addition, EphA7 also has a dual role of tumor promoter and tumor suppressor. It can participate in cell proliferation, migration and apoptosis through various mechanisms, and afect tumor diferentiation, staging and prognosis. EphA7 may be a potential diagnostic marker and tumor treatment target (PMID:35112312).
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