Ephrin B3 Polyclonal antibody, PBS Only

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• Ephrin B3 Polyclonal antibody, PBS Only (55080-1-PBS)

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  WB analysis using 55080-1-AP (same clone as 55080-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55080-1-AP (Ephrin B3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55080-1-PBS in a different storage buffer formulation.

Ephrin B3 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 55080-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

EFNB3, EFL6, EPLG8, LERK 8, LERK8

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Product Information

55080-1-PBS targets Ephrin B3 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: ephrin-B3
• Calculated Molecular Weight: 36 kDa
• Observed Molecular Weight: 45-50 kDa
• GenBank Accession Number: NM_001406
• Gene Symbol: EFNB3
• Gene ID (NCBI): 1949
• RRID: AB_3743199
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q15768
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Ephrin-B3 is a transmembrane ligand that binds primarily to EphB receptors to mediate bidirectional cell signaling, crucial for neural development, axon guidance, and synaptic plasticity. Highly expressed in the brain and spinal cord, it acts as a midline repellent to guide axonal pathfinding (PMID: 16951161). Ephrin‑B3 is important in the regulation of cell proliferation, differentiation and migration via cell‑cell contact, and can activate the reelin pathway during brain development. The band of ephrin-B3 was identical to phosphorylated ephrin-B at 50 kDa (PMID: 16951161, 21447033).