FANCA Polyclonal antibody, PBS Only

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• FANCA Polyclonal antibody, PBS Only (11975-1-PBS)

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  WB analysis of HeLa cells using 11975-1-AP (same clone as 11975-1-PBS)

  WB results of FANCA (11975-1-AP, 1:500) with si-control and si-FANCA transfected HeLa cells. This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  WB analysis using 11975-1-AP (same clone as 11975-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11975-1-AP (FANCA antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 11975-1-AP (same clone as 11975-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 11975-1-AP (FANCA Antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 11975-1-AP (same clone as 11975-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 11975-1-AP (FANCA Antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 11975-1-AP (same clone as 11975-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 11975-1-AP (FANCA antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  IHC staining of human cervical cancer using 11975-1-AP (same clone as 11975-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 11975-1-AP (FANCA antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse intestine using 11975-1-AP (same clone as 11975-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse intestine tissue slide using 11975-1-AP (FANCA antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse thymus using 11975-1-AP (same clone as 11975-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse thymus tissue slide using 11975-1-AP (FANCA antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  IHC staining of rat small intestine using 11975-1-AP (same clone as 11975-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat small intestine tissue slide using 11975-1-AP (FANCA antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

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  IHC staining of rat testis using 11975-1-AP (same clone as 11975-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat testis tissue slide using 11975-1-AP (FANCA antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11975-1-PBS in a different storage buffer formulation.

• Featured Product
• KD/KO Validated

FANCA Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 11975-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

FANCH, FAH, FACA, FAA, FA1

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Product Information

11975-1-PBS targets FANCA in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag2598

  Product name: Recombinant human FANCA protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-297 aa of BC008979

  Sequence: MSDSWVPNSASGQDPGGRRRAWAELLAGRVKREKYNPERAQKLKESAVRLLRSHQDLNALLLEVEGPLCKKLSLSKVIDCDSSEAYANHSSSFIGSALQDQASRLGVPVGILSAGMVASSVGQICTAPAETSHPVLLTVEQRKKLSSLLEFAQYLLAHSMFSRLSFCQELWKIQSSLLLEAVWHLHVQGIVSLQELLESHPDMHAVGSWLFRNLCCLCEQMEASCQHADVARAMLSDFVQMFVLRGFQKNSDLRRTVEPEKMPQVAVDVLQRMLIFALDALAAGVQEESSTHKIVRC

• Full Name: Fanconi anemia, complementation group A
• Calculated Molecular Weight: 163 kDa
• Observed Molecular Weight: 163 kDa
• GenBank Accession Number: BC008979
• Gene Symbol: FANCA
• Gene ID (NCBI): 2175
• RRID: AB_2101786
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O15360
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

FANCA, also named as FAA, FACA and FANCH, is a DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. It's involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.