GGTLC2 Polyclonal antibody, PBS Only

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• GGTLC2 Polyclonal antibody, PBS Only (18191-1-PBS)

• 

  WB analysis using 18191-1-AP (same clone as 18191-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18191-1-AP (GGTLC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18191-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 18191-1-AP (same clone as 18191-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18191-1-AP (GGTLC2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18191-1-PBS in a different storage buffer formulation.

GGTLC2 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 18191-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTL4, Glutathione hydrolase light chain 2

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Product Information

18191-1-PBS targets GGTLC2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag12911

  Product name: Recombinant human GGTLC2 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-218 aa of BC069534

  Sequence: MTSEFFAAQLRAQISDDTTHPISYYKPEFYTPVDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNDEMDDFSSPNITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQPPSHADHTPMPQAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

• Full Name: gamma-glutamyltransferase light chain 2
• Calculated Molecular Weight: 218 aa, 24 kDa
• Observed Molecular Weight: 24 kDa
• GenBank Accession Number: BC069534
• Gene Symbol: GGTLC2
• Gene ID (NCBI): 91227
• RRID: AB_3741947
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q14390
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

GGT is a protease anchored to the cell membrane, consisting of a light chain and a heavy chain. GGTLC2 (Glutathione hydrolase light chain 2), also known as GGTL4, a constituent of the GGT family, has been characterized as an antioxidant gene, with emerging evidence indicating a potential link between its expression levels and sarcoma patient outcome (PMID: 40191433). Studies have shown that GGTLC2 is highly expressed in gastric cancer, promoting cell proliferation, invasion, and migration while inhibiting apoptosis and ferroptosis.