Recombinant Human LILRA6 protein (rFc Tag)

Species

Human

Purity

>90 %, SDS-PAGE

Tag

rFc Tag

Activity

not tested

Cat no : Eg3776

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Validation Data Gallery

• 

  Purity of Recombinant Human LILRA6 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

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Product Information

• Purity: >90 %, SDS-PAGE
• Endotoxin: <0.1 EU/μg protein, LAL method
• Activity:

  Not tested

• Expression: HEK293-derived Human LILRA6 protein Gly24-Asn447 (Accession# Q6PI73-1) with a rabbit IgG Fc tag at the C-terminus.
• GeneID: 79168
• Accession: Q6PI73-1
• PredictedSize: 72.6 kDa
• SDS-PAGE: 80-90 kDa, reducing (R) conditions
• Formulation: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
• Reconstitution: Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
• Storage Conditions:
  It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

Leukocyte immunoglobulin-like receptor subfamily A member 6 belongs to the leukocyte immunoglobulin-like receptors (LILRs, also known as ILTs and LIRs). Among 11 family members, inhibitory LILRB3 (ILT5, LIR3) and activating LILRA6 (ILT8) represent a unique homologous receptor pair characterized by highly polymorphic ectodomains.

References:

1. Bashirova AA, et al. (2023) Immunogenetics. 75(3):263-267.
2. Lopez-Alvarez MR, et al. (2014) Immunogenetics. 66:73–83.