L-VOCC Polyclonal antibody

L-VOCC Polyclonal Antibody for IF, IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 21774-1-AP

Synonyms

CACH2, CACN2, CACNA1C, CACNL1A1, CaV1.2, CCHL1A1, L VOCC, TS



Tested Applications

Positive IHC detected inmouse brain tissue, rat brain tissue, mouse liver tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inmouse brain tissue

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:200-1:800
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 5 publications below

Product Information

The immunogen of 21774-1-AP is L-VOCC Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Cited Reactivity rabbit, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen L-VOCC fusion protein Ag16455
Full Name calcium channel, voltage-dependent, L type, alpha 1C subunit
Calculated molecular weight 2135 aa, 239 kDa
GenBank accession numberBC146846
Gene symbol CACNA1C
Gene ID (NCBI) 775
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
IHC protocol for L-VOCC antibody 21774-1-APDownload protocol
IF protocol for L-VOCC antibody 21774-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratWB

Phytomedicine

Protective role and mechanism of snakegourd peel against myocardial infarction in rats.

Authors - Guanlin Yang
ratWB

Life Sci

Prenatal hypoxia attenuated contraction of offspring coronary artery associated with decreased PKCβ Ser660 phosphorylation and intracellular calcium.

Authors - Xueyi Chen
ratWB

J Endocrinol

In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.

Authors - Hongyu Su
rabbitWB

Cardiovasc Drugs Ther

Effects of Angiotensin Receptor-Neprilysin Inhibitor in Arrhythmogenicity Following Left Atrial Appendage Closure in an Animal Model.

Authors - Wen-Han Cheng
ratWB

Mol Nutr Food Res

Quercetin Attenuates Ethanol-Induced Iron Uptake and Myocardial Injury by Regulating the Angiotensin II-L-Type Calcium Channel.

Authors - Xiaoping Guo

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Wu (Verified Customer) (07-16-2021)

Works good for IHC assay

  • Applications: Immunohistochemistry
  • Primary Antibody Dilution: 1:100
  • Cell Tissue Type: glandular lumen
L-VOCC Antibody Immunohistochemistry validation (1:100 dilution) in glandular lumen (Cat no:21774-1-AP)