LAMB3 Recombinant antibody, PBS Only

LAMB3 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA

Cat No. 85055-4-PBS
Clone No.242442A8

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, IHC, Indirect ELISA

Laminin B1k chain, 242442A8, Epiligrin subunit bata, Kalinin B1 chain, Kalinin subunit beta

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Product Information

85055-4-PBS targets LAMB3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, rat samples.

Tested Reactivity human, rat
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen LAMB3 fusion protein Ag25192 Predict reactive species
Full Name laminin, beta 3
Calculated Molecular Weight 1172 aa, 130 kDa
Observed Molecular Weight130-140 kDa
GenBank Accession NumberBC075838
Gene Symbol LAMB3
Gene ID (NCBI) 3914
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ13751
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

LAMB3 (β3 subunit of laminin) is an important extracellular matrix protein, which plays an important role in cell adhesion, migration, signal transduction and the formation and stability of basement membrane. LAMB3 plays a key role in the basement membrane of skin and mucosa, maintaining the adhesion between epidermis and dermis. Its abnormal function will lead to skin bullous disease (such as severe borderline epidermolaxis, sJEB), which is characterized by blisters and ulcers on skin and mucosa. LAMB3 is highly expressed in many cancers, including pancreatic ductal adenocarcinoma (PDAC), lung cancer, head and neck squamous cell carcinoma, etc., which is closely related to the proliferation, invasion and metastasis of tumor cells.

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