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LPHN1 Polyclonal antibody, PBS Only

LPHN1 Polyclonal Antibody for IHC, IF-P, Indirect ELISA

Cat No. 30142-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, IF-P, Indirect ELISA

CIRL-1, CIRL1, CIRL 1, Calcium-independent alpha-latrotoxin receptor 1, Adhesion G protein-coupled receptor L1

Formulation:  PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

30142-1-PBS targets LPHN1 in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag31093

Product name: Recombinant human LPHN1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 400-500 aa of NM_001008701

Sequence: DPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVE

Predict reactive species
Full Name latrophilin 1
Calculated Molecular Weight 163 kDa
GenBank Accession NumberNM_001008701
Gene Symbol LPHN1
Gene ID (NCBI) 22859
RRIDAB_3742328
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDO94910
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

Latrophilin-1 (LPHN1) was isolated as the main high-affinity receptor for α-latrotoxin from black widow spider venom, a powerful presynaptic secretagogue (PMID: 30967757). aGPCR latrophilin 1 (ADGRL1/LPHN1) is involved in controlling energy balance and food intake. Although this receptor is present in adipocytes and many neurons, where it is essential for axon growth cone formation and neuronal. It is present in Adipocytes and many neurons, where it is essential for Axon growth cone formation and neuronal function (PMID: 38664368).

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